TI: Further investigations on the antiviral activities of medicinal plants of Togo.
AU: Hudson-JB; Anani-K; Lee-MK; Souza-C-de; Arnason-JT; Gbeassor-M; de-Souza-C
AD: Department of Pathology and Laboratory Medicine, Heather Pavilion, C Floor,
2733 Heather Street, Vancouver V5Z 1M9, BC, Canada.
SO:
Pharmaceutical-Biology. 2000, 38: 1, 46-50; 10 ref.
PY: 2000
LA: English
AB: Further studies were done on the antiviral activities of 10 species of
Togolese medicinal plants, previously shown to possess activity against herpes
simplex virus (HSV). The dominant activity in all cases was virucidal (direct
inactivation of virus particles), although Adansonia digitata extracts also
appeared to have intracellular antiviral activities as well, which could indicate
the presence of multiple antiviral compounds, or a single compound with multiple
actions. In the 7 most active extracts, anti-HSV activity was considerably enhanced
by light, especially UVA (long wavelength UV), although they all showed dark
antiviral activity as well. Thus, all the extracts contained antiviral photosensitizers.
In all tests, the root-bark and leaf extracts of A. digitata were the most potent.
DE: medicinal-plants; plant-extracts; antiviral-plants; antiviral-properties;
roots-; bark-; leaves-; light-; plant-composition
OD: Adansonia-; Adansonia-digitata; viruses-; herpes-simplex-virus
GE: Togo-
BT: Bombacaceae; Malvales; dicotyledons; angiosperms; Spermatophyta; plants;
Adansonia; human-herpesvirus; Herpesviridae; viruses; West-Africa; Africa-South-of-Sahara;
Africa; Least-Developed-Countries; Developing-Countries; ACP-Countries; Francophone-Africa
CC: FF000; VV450; SS200; KK100; KK540; HH405; HH420
CD: Plant-Science-General; Animal-and-in-vitro-Models-for-Pharmaceuticals; Non-food/Non-feed-Plant-Products;
Forests-and-Forest-Trees-Biology-and-Ecology; Non-wood-Forest-Products; Pesticides-and-Drugs-Control;
Pesticides-and-Drugs-Chemistry-and-Formulation
PT: Journal-article
UD: 20000928
AN: 20000311192
Record 7 of 91
in CAB Abstracts 2000/08-2001/04