TI: Anti-inflammatory, analgesic and antipyretic effects of the fruit pulp of Adansonia digitata.
AU: Ramadan-A; Harraz-FM; El-Mougy-SA
AD: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, King Saud University, Qassim, Buriedah PO Box 1482, Saudi Arabia.
SO: Fitoterapia. 1994, 65: 5, 418-422; 18 ref.
PY: 1994
LA: English

AB: A. digitata is used in folk medicine as an antipyretic and febrifuge. In an experiment with Wistar rats, the aqueous extract of A. digitata fruit pulp (prepared from Sudanese fruits) exhibited significant antiinflammatory and antipyretic activities at both 400 and 800 mg/kg p.o. Oral administration of the extract to Balb/c mice at 800 mg/kg had a significant analgesic effect, and a slight analgesic effect at 400 mg/kg. In an acute toxicity test with mice, i.p. administration of the extract gave an LD50 value of 8000 mg/kg. Phytochemical screening of the fruit pulp indicated the presence of sterols and/or triterpenes, saponins, tannins, carbohydrates and glycosides.

DE: fruits-; medicinal-properties; medicinal-plants; animal-models; toxicity-; plant-composition; plant-extracts; pharmacology-; toxicology-; sterols-; triterpenoids-; saponins-; tannins-; carbohydrates-; screening-; multipurpose-trees
OD: Bombacaceae-; rats-; mice-; Adansonia-digitata; animals-
GE: Sudan-
ID: antiinflammatory-properties; analgesic-properties; antipyretic-properties
BT: plants; trees; woody-plants; Spermatophyta; Malvales; dicotyledons; angiosperms; Muridae; Rodents; mammals; vertebrates; Chordata; animals; Adansonia; Bombacaceae; ACP-Countries; East-Africa; Africa-South-of-Sahara; Africa; Least-Developed-Countries; Developing-Countries
CC: FF040; LL900; VV800; KK540; KK600
CD: Plant-Composition; Animal-Toxicology,-Poisoning-and-Pharmacology; Human-Toxicology,-Poisoning-and-Pharmacology; Forest-Products-Miscellaneous,-including-Minor-Forest-Products; Agroforestry
PT: Journal-article
IS: 0367-326X
UD: 960116
AN: 950304584